Researcher

    Mathieu Dehaes , Ph.D.

    mathieu.dehaes@umontreal.ca
    Mathieu Dehaes
    Research Axis
    Brain and Child Development Axis
    Research Theme
    Neurodevelopmental diseases
    Address
    CHUSJ - Centre de Recherche Office 2.17.007

    Phone
    514 345-4931 #5137

    Online

    Title

    • Associate Professor, Department of Radiology and Institut de génie biomédical, Université de Montréal, Montréal, Canada (see Academic Profile), 2015
    • Scientist, Brain and Child Development Axis, CHU Sainte-Justine Research Center, Montréal, Canada, 2013

    Internship opportunities

    Open positions are available for several projects. Please contact Pr. Dehaes for more details.

    Education

    • Instructor (Junior Faculty), Department of Pediatrics, Harvard Medical School, Boston, USA
    • Postdoctoral Fellow, Department of Pediatrics, Harvard Medical School, Boston Children's Hospital, Boston, USA
    • Postdoctoral Fellow, Faculty of Medicine, Université Paris XI and Hôpital La Pitié-Salpêtrière, Paris, France
    • Postdoctoral Fellow, Faculty of Medicine, Université de la Picardie Jules Verne and Hôpital Amiens Nord, Amiens, France
    • Ph.D., Biomedical Engineering, École Polytechnique de Montréal, Montréal, Canada
    • M.Sc., Applied Mathematics, Université de Montréal, Montréal, Canada
    • B.Sc., Mathematics and Computer Sciences, Université du Québec à Chicoutimi, Chicoutimi, Canada
    • Certificat, Business Administration, Université du Québec à Chicoutimi, Chicoutimi, Canada 

    Research Interests

    My research program focuses on the development of biomedical imaging and spectroscopy technologies and methods suited for a variety of pre- and postnatal applications in human and animal. These developments are used to study the structure and function of organs including the brain and retina as well as for biofluids and tumors.

    Some of these developments are applied in populations at risk of brain injury associated with perinatal asphyxia, congenital heart disease and prematurity.

    Research Topics

    • Imaging and spectroscopy methods and technology
    • Data acquisition and signal/image analysis
    • Near infrared spectroscopy (NIRS)
    • Diffuse correlation spectroscopy (DCS)
    • Raman spectroscopy 
    • Optical coherence tomography (OCT)
    • Magnetic resonance imaging (MRI)
    • Electroencephalography (EEG)

    Applications

    • Brain imaging
    • Retina imaging
    • Spectroscopy of biofluids
    • Fetal, neonatal and pediatric imaging
    • Small animal imaging

    Awards and Distinctions

    • FRQS Research scholar award (Junior 2)
    • FRQS Research scholar award (Junior 1)
    • Faculty Career Development Award (Declined), Boston Children's Hospital
    • William Randolph Hearst Foundation, Harvard Medical School
    • Isabelle and Leonard H. Goldenson Foundation, Harvard Medical School
    • FRQNT Postdoctoral Scholarship
    • PhD Thesis selected for the Dean's Honour List, Polytechnique Montréal

    Publications

    For complete list of publications, see PubMed >> and Google Scholar >>

    1. Erdenedalai K, Maltais-Tariant R, Dehaes M* and Boudoux C*. (2024). An experimentally and numerically validated, open-source Monte Carlo simulator for optical coherence tomography. Biomed Opt Express. 15(2): 624-640. Link, not yet indexed in PubMed.
    2. Kiaei DS, El-Jalbout R, Decarie JC, Perreault S* and Dehaes M*. (2024). Development of a semi-automatic segmentation technique based on mean magnetic resonance imaging intensity thresholding for volumetric quantification of plexiform neurofibromas. Heliyon. 10(1): e23445. PMID: 38173515.
    3. Maltais-Tariant R, Becerra-Deana RI, Brais-Brunet S, Dehaes M* and Boudoux C*. (2023). Speckle contrast reduction through the use of a modally-specific photonic lantern for optical coherence tomography. Biomed Opt Express. 14(12): 6250-6259. Link, not yet indexed in PubMed.
    4. Charbonneau L, Chowdhury RA, Marandyuk B, Poirier N, Miró J, Birca A, Nuyt AM, Raboisson MJ* and Dehaes M*. (2023). Fetal cardiac and neonatal cerebral hemodynamics and oxygen metabolism in transposition of the great arteries. Ultrasound Obstet Gynecol. 61: 346-355. PMID: 36565437.
    5. Côté Corriveau G, Simard MN, Beaulieu O, Chowdhury RA, Gagnon MM, Gagnon M, Ledjiar O, Bernard C, Nuyt AM, Dehaes M* and Luu TM*. (2023). Association between neurological examination at term-equivalent age and cerebral hemodynamics and oxygen metabolism in infants born preterm. Front Neurosci. 17: 1105638. PMID: 36937667
    6. Mahdi Z, Marandyuk B, Desnous B, Liet AS, Chowdhury RA, Birca V, Décarie JC, Tremblay S, Lodygensky GA, Birca A, Pinchefsky E* and Dehaes M*. (2022). Opioid analgesia and temperature regulation are associated with EEG background activity and MRI outcomes in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia. Eur J Paediatr Neurol. 39: 11-18. PMID: 35598572.
    7. Brais-Brunet S, Heckel E, Kanniyappan U, Chemtob S, Boudoux C, Joyal JS and Dehaes M. (2021). Morphometric and Microstructural Changes during Murine Retinal Development Characterized using in-vivo Optical Coherence Tomography. Investig Ophthalmol Vis Sci. 62(13): 20-20. PMID: 34698774.
    8. Janaillac M, Beausoleil TP, Raboisson MJ, Barrington KJ, Karam O, Dehaes M* and Lapointe A*. (2018). Correlations between near-infrared spectroscopy, perfusion index, and cardiac outputs in extremely preterm infants in the first 72 hours of life. Eur J Ped. 177(4): 541-550. PMID: 29374830.
    9. Beausoleil TP, Janaillac M, Barrington KJ, Lapointe A* and Dehaes M*. (2018). Cerebral oxygen saturation and peripheral perfusion in the extremely premature infant with intraventricular and/or pulmonary hemorrhage early in life. Sci Rep. 8(6511): 1-13. PMID: 29695729.
    10. Auger H, Bherer L, Boucher E, Hoge R, Lesage F and Dehaes M. (2016). Quantification of extra- cerebral and cerebral hemoglobin concentrations during physical exercise using time-domain near infrared spectroscopy. Biomed Opt Express. 7(10): 3826-3842. PMID: 27867696.
 

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