Françoise Le Deist , M.D. , Ph.D.
    Françoise Le Deist
    Research Axis
    Immune Diseases and Cancer Axis
    Research Theme
    Immune diseases: mechanisms, new therapeutic approaches and disease outcomes

    514 345-4931 #3534

    514 345-7860


    • Full Professor, Department of Microbiology and Immunology, University of Montreal.
    • Researcher, CHU Sainte-Justine Research Center.


    • PhD, Université Paris VII, 1983.
    • MD, Université Paris VI, 1982.

    Research Interests

    From 1988 to 2005 I was in charge of the Centre d'étude des déficits immunitaires at the Necker Hospital for Sick Children in Paris (France). During this period I studied the physiopathology of certain hereditary immune diseases including immunodeficiency and autoimmune diseases.

    I have continued my career as a researcher at the CHU Sainte-Justine Research Center since 2005 where my interests have focused on:

    • Immune reconstitution following hematopoietic stem cell transplant.
    • Innate immunity and infections: Are certain infections observed in the population due to a specific genetically determined susceptibility?
    • Hereditary immunodeficiencies: elucidating novel mechanisms responsible for still poorly understood immunodeficiency.
    • Immune reconstitution after hematopoietic stem cell transplantation: Hematopoietic stem cell transplantation constitutes an in vivo lymphocyte differentiation model.
    • Pharmacodynamics of immunosuppression: understanding the mechanisms behind the variability in susceptibility to treatments prescribed to organ transplant patients.


    • Lapeyraque AL, Durrieu V, Phan V, Alvarez F, Raboisson MJ, Haddad E, Brito RM, Lajeunesse J, Théorêt Y, Le Deist F. New tools for the pharmacodynamic monitoring of immunosuppressive drugs in pediatric kidney, heart and liver transplant patients. 11th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology, Montréal, 3-8 octobre, 2009.
    • Rottembourg D, Le Deist F, Carel JC Lacroix A, Mallone R, Deal C. T cell epitope identification in auto-immune adrenal deficiency. Annual Meeting of The Endocrine Society, Washington D. C., juin 2009.

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