Sze Man TSE , M.D. , FRCPC
    Sze Man TSE
    Research Axis
    Infectious Diseases and Acute Care Axis
    Research Theme
    Respiratory health
    CHUSJ - Centre de Recherche

    514 345-4931 #3691

    514 345-4804


    • Clinical Assistant Professor, Department of Pediatrics, University of Montréal
    • Pediatric Pulmonologist, CHU Sainte-Justine


    • 2012, MPH, Harvard School of Public Health, Boston, USA
    • 2012, Research fellowship, Channing Laboratory, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
    • 2012, Fellowship in pediatric respirology, Massachusetts General Hospital, Harvard University, Boston, USA
    • 2009, Residency in pediatrics, Montreal Children's Hospital, McGill University Health Center, Montréal, Canada
    • 2006, MDCM McGill University, Faculty of medicine, Montréal, Canada

    Career Summary

    Asthma is an inflammatory airways disease affecting approximately 10% of Canadian children. It is a heterogeneous condition with different clinical presentations and different risk factors for its development. There is also an important variability in the medication response between individuals. My research interests primarily focuses on asthma epidemiology and asthma pharmacogenetics, specifically related to genetic and non-genetic risk factors for asthma and response to medications used to treat asthma as well as the use of clinical tests (e.g. pulmonary function tests, biomarkers, lung imaging) to differentiate the subgroups of asthma. Ultimately, the identification of these risk factors and asthma subgroups may allow a more personalized treatment of children affected by asthma. 

    Research topics

    • Pediatric asthma
    • Pharmacogenetics
    • Risk factor for asthma and wheezing development
    • Risk factor for medication response in asthma
    • Epidemiology

    Awards and Distinctions

    • 2012, Travel award, American Thoracic Society annual meeting 2012
    • 2008, American Academy of Pediatrics Resident Research Grant. Prevalence of asthma and obstructive sleep apnea in obese adolescents with and without the metabolic syndrome


    1. 2014 Asthma in the PICU: risk factors for readmissions and long-term follow-up. Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) meeting 2014, Montréal, Canada.
    2. 2013 "Facteurs de risque associés au wheezing: différence entre les sexes". Scientific meeting of the CHU Sainte-Justine research center. Montréal, Canada.
    3. 2013 "Effets des statines sur les exacerbations d'asthme: l'utilisation du score de propension". Scientific meeting of the Health Outcomes research axis, CHU Sainte-Justine. Montréal, Canada.
    4. 2013 "Those difficult teenage years: gender differences for dysanaptic growth and asthma". Canadian Respiratory Conference 2013, Québec, Canada.


    1. Tse SM, Coull BA, Sordillo JE, Datta S, Gold DR. Gender- and age-specific risk factors for wheeze from birth through adolescence. Pediatr Pulmonol. 2014. Oct 27. Epub.
    2. Tse SM, Charland SL, Stanek E, Herrera V, Goldfarb S, Litonjua AA, Weiss ST, Wu AC. Statin use in asthmatics on inhaled corticosteroids is associated with decreased risk of emergency department visits. Curr Med Res Opin. 2014 Apr;30(4):685-93. Epub 2013 Dec 18.
    3. Tse SM, Li L, Butler MG, Fung V, Kharbanda EO, Larkin EK, Vollmer WM, Miroshnik I, Rusinak D, Weiss ST, Lieu T, Wu A. Statin exposure is associated with decreased asthma-related emergency department visits and oral corticosteroid use. Am J Respir Crit Care Med. 2013 Nov 1; 188(9):1076-82.
    4. Tse SM, Gold DR, Sordillo JE, Hoffman EB, Gillman MW, Rifas-Shiman SL, Fuhlbrigge AL, Tantisira KG, Weiss ST, Litonjua AA. Diagnostic accuracy of the bronchodilator response in children. J Allergy Clin Immunol. 2013 Sep; 132(3):554-559
    5. Tse SM, Kelly HW, Litonjua AA, Van Natta ML, Weiss ST, Tantisira KG on behalf of the CAMP research group. Corticosteroid use and bone mineral density in children with asthma: effect modification by vitamin D. J Allergy Clin Immunol. 2012 Jul; 130(1):53-60.

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