Philippe Major , M.D.
    Philippe Major
    Research Axis
    Brain and Child Development
    Research Theme
    Neurodevelopmental diseases
    CHUSJ Office 5415.D



    • Associate professor, Department of Pediatrics, Faculty of Medicine, University of Montréal, 2014


    • Fellowship in pediatric neurology and tuberous sclerosis complex, Massachusetts General Hospital, Harvard University, 2006-2008
    • Specialty in pediatric neurology, CHU Ste-Justine, Université de Montréal, 2001-2006

    Career Summary

    Dr Philippe Major finished his residency in Pediatric Neurology at the CHU Sainte-Justine in 2006. He then completed a fellowship in Pediatric Epilepsy at the Massachusetts General Hospital in 2008, where he was responsible for the Tuberous Sclerosis Complex (TSC) Clinic. Since 2008, he leads the first Canadian TSC clinic.  He is interested about the many clinical manifestations of this disease, in particular about its neurological impacts (epilepsy, intellectual and developmental delay, autistic spectrum disorder, psychiatric manifestations).

    His research projects focus also on many forms of epilepsy, from benign to refractory types.

    Since 2012, Dr Major has also been director of the residency program in pediatric neurology.  

    Awards and Distinctions

    • Claude Roy Prize for the highest achievement in research during residency at the CHU Sainte-Justine, 2006
    • Canadian Society for Clinical Research/Canadian Institutes of Health Research Resident Research Prize, 2005
    • First Prize - Poster Presentation, XVIIIth Student Congress of the CHU Sainte-Justine Research Center, 2003

    Selected Publications

    1. Major P, Lortie A, Dehaes M, Lodygensky GA, Gallagher A, Carmant L, Birca A.  Periictal activity in cooled asphyxiated neonates with seizures. Seizure. 2017 Apr;47:13-16
    2. Kaseka ML, Bitton JY, Décarie JC, Major P. Predictive Factors for Epilepsy in Pediatric Patients With Sturge-Weber Syndrome.  Pediatr Neurol. 2016 Nov;64:52-58
    3. Goyer I, Dahdah N, Major P. Use of mTOR inhibitor everolimus in three neonates for treatment of tumors associated with tuberous sclerosis complex. Pediatr Neurol. 2015 Apr;52(4):450-3
    4. Major P. Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex. Aging (Albany NY). 2011 Mar;3(3):189-91.
    5. Birca A, Mercier C, Major P. Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex. J Neurosurg Pediatr. 2010 Oct;6(4):381-4. 
About this page
Edited by Hoffmann Maude

Created on 9/18/2014
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