Researcher

Title

• Clinician Researcher, CHU Sainte-Justine Research Center
• Director, Canadian Neonatal Brain Platform
• Associated researcher, Institut de cardiologie de Montréal (ICM)
• Clinical Associate Professor, Paediatrics, Université de Montréal

Fellowship opportunity(ies)

• Imaging - Postdoctoral fellowship
  Contact: Yang Ding

• Paediatrics residency, Medicine Faculty of Geneva, Geneva, Switzerland
• Neonatology Fellowship, University of Washington, St.-Louis, Missouri
• Research Fellowship in Neuro-neonatology, University of Geneva, Switzerland

Dr. Lodygensky is interested in the neurological trajectory of newborns at risk of brain damage, seeking to improve cerebral monitoring in acute periods, identifying neuronal disturbers and introducing neuroprotective neonatal strategies. In its fundamental research laboratory, activities include quantifying the lesion load and evaluating the efficacy of neuroprotective therapies using multimodal MRI and new techniques in rodent optics, correlated with histological, biochemical and behavioral studies. In addition, with the Canadian Neonatal Brain Platform, which was established in September 2015, Dr. Lodygensky seeks to enhance neonatal neuro-imaging research in Canada by pooling the expertise of more than 30 collaborators.

• MRI
• DTI
• MRS
• Neuro-inflammation
• Neuro-Neonatology

Awards and Distinctions

• 2013, Clinical Research Scholar, FRQS
• 2009-2011, Clinician-Researcher award - Programme de relève académique suisse « Special Program University Medicine » of the Fonds national suisse
• 2008-2011, Scientific Clinic Manager Award, University of Geneva
• 2005-2006, Fonds de perfectionnement des hôpitaux universitaires de Genève
• 2005, Tissot price for the thesis « Atlas interactif d’Ophtalmologie », Geneva

Presentations

• Development of biomarkers for perinatal inflammatory brain injury, Child Health and Human Development Program, Seminar, Research Institute of the McGill University Health Centre, Montréal Canada 2017
• Imagerie néonatale et applications : exemple de l'encéphalopathie néonatale. Assemblée annuelle des néonatalogistes du Québec, Montreal, Canada, 2016
• « Neonatal Cooling » indications et résultats. Journées annuelles du département d’obstétrique- gynécologie, Mont-Tremblant, Canada, Mars 2016
• Identification of pre- and postnatal inflammatory brain injury by MRI: lessons from animal models. Canadian National Perinatal Research Meeting, Banf, February 2014
• Visioconférence Réseau mère-enfant : Approche de la convulsion néonatale, Montraal 2013
• Douglas Institute, Is it to small to image, the place of high-field MRI, Verdun Canada 2012
• University of Montreal, Use of high-field MRI in animal research, Sainte-Hyacinthe, Canada, 2012
• 9th National Pediatric Update, Koweït, Koweït City, November 2011
• Neonatal Asphyxia, MRI in the NICU, Neonatal Adaptation, Neonatal Hypotonia. Hot topics in Neonatal Medicine, Jeddah, Arabie Saoudite, February 2011.
• Clinical Application of MRI in Preterm & Term infants, Neonatal Stroke; Cerebral MRI workshop, aEEG use in the NICU (ateliers)
• University of Geneva, Neonatal cooling, Hot and cool topics, novembre 2010, Geneva, Switzerland
• CHU Sainte-Justine : Définition IRM de l’atteinte inflammatoire du la substance blanche du cerveau en développement, Montreal, Canada, 2010
• University of Geneva, Rôle de VEGF dans le développement cérébral ainsi qu’en cas de lésion, Geneva, Switzerland, 2010
• University of Geneva, From Cortex to class room symposium, DWI chez le rat immature lors d’une atteinte inflammatoire. Geneva, Switzerland, 2009

Selected Publications

• Long-term attention deficits combined with subcortical and cortical structural central nervous system alterations in young adults born small for gestational age. Sabrina Suffren, Diego Angulo, Yang Ding, Pablo Reyes, Jorge Marin, Jose T. Hernandez, Nathalie Charpak, Gregory A. Lodygensky, Early Human Development. Doi 10.1016/j.earlhumdev.2017.04.016
• Neonatal microglia: The cornerstone of brain fate. Pierre WC, Smith PL, Londono I, Chemtob S, Mallard C, Lodygensky GA. Brain Behav Immun. 2017 Jan;59:333-345. 
• Association between early administration of high-dose erythropoietin in preterm infants and brain MRI abnormality at term-equivalent age. Leuchter RH, Gui L, Poncet A, Hagmann C, Lodygensky GA, Martin E, Koller B, Darqué A, Bucher HU, Hüppi PS. JAMA. 2014 Aug 27;312(8):817-24. doi: 10.1001/jama.2014.9645.
• Definition and quantification of acute inflammatory white matter injury in the immature brain by MRI/MRS at high magnetic field. Lodygensky GA, Kunz N, Perroud E, Somm E, Mlynarik V, Hüppi PS, Gruetter R, Sizonenko SV. Pediatr Res. 2014 Mar;75(3):415-23. doi: 10.1038/pr.2013.242. Epub 2013 Dec 17.
• In vivo assessment of myelination by phase imaging at high magnetic field. Lodygensky GA, Marques JP, Maddage R, Perroud E, Sizonenko SV, Hüppi PS, Gruetter R. Neuroimage. 2012 Feb 1;59(3):1979-87. doi: 10.1016/j.neuroimage.2011.09.057. Epub 2011 Oct 1.