Research Group on Blood Transfusion

Association between Transfusion-Related Hypotensive Reactions (TRHRs) and Kinins in Platelet Concentrates (PCs)

The aim of this project is to measure the level of bradykinins in platelet concentrates that have caused a hypotensive reaction and compare them with bradykinin levels in platelet concentrates that have not caused a post-transfusion hypotensive reaction.

Main Objectives

If bradykinin levels are higher in platelet concentrates that have caused a drop in blood pressure, this could lead to therapeutic interventions to prevent or minimize these reactions.

Preliminary results

Analysis of the results is in progress.

  • Principal Investigator of the Study: Dre Marisa Tucci
  • Investigator at CHU Sainte-Justine: Dre Marisa Tucci
  • Source of funding: Fonds de Recherche du Québec - Santé (FRQS)
  • Study Design: Étude biologique
  • Number of Participants: 168


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Updated on 10/8/2014
Created on 10/8/2014
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