Research Group on Blood Transfusion
Association between Transfusion-Related Hypotensive Reactions (TRHRs) and Kinins in Platelet Concentrates (PCs)
The aim of this project is to measure the level of bradykinins in platelet concentrates that have caused a hypotensive reaction and compare them with bradykinin levels in platelet concentrates that have not caused a post-transfusion hypotensive reaction.
Main Objectives
If bradykinin levels are higher in platelet concentrates that have caused a drop in blood pressure, this could lead to therapeutic interventions to prevent or minimize these reactions.
Preliminary results
Analysis of the results is in progress.
-
Principal Investigator of the Study: Dre Marisa Tucci
-
Investigator at CHU Sainte-Justine: Dre Marisa Tucci
-
Source of funding: Fonds de Recherche du Québec - Santé (FRQS)
-
Study Design: Étude biologique
-
Number of Participants: 168