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Clinical research study in children and adolescents with birch pollen allergy

Principal investigator at CHU Sainte-Justine 

Dr. Anne DesRoches, allergist

The TreeTop Study will involve around 1000 participants in study centres across Europe and Canada and 103 in Quebec.  You will receive a medical diagnosis of your allergy and support symptom control.  This study will investigate the efficacy and safety of a tree pollen immunotherapy tablet in children and teenagers with birch pollen allergy.  This tablet has already been approved for use in adults.

Who can participate?

  • Be aged 5-17 years
  • Be allergic to birch pollen
  • Experience moderate to severe allergic rhinitis and/or conjunctivitis

There are other criteria that must be met to join the Tree Top Study which will be discussed with you.         

Who can not participate?

  • Have a relevant clinical history of a perennial allergy (i.e. pet, molds, etc.) that you are exposed to regularly 
  • Current treatment with any allergy immunotherapy product
  • Have any clinical deterioration of asthma (i.e. asthma exacerbation) that resulted in emergency treatment, hospitalization or treatment with systemic corticosteroids within 3 months prior to randomization

What should they expect in terms of process and engagement?

Your participation in the study will last a maximum of 17 months.  There will be 6 planned visits to the study centre and 4 telephone call to discuss your health with the study doctor or nurse.

Why participate?

  • Study related exams and allergy medication at no cost
  • Reimbursement for travel for clinic visits

Contact information

If you would like additional information regarding this study, or if you would like to determine if your child may be eligible to participate, please contact Isabelle Boisvert by email at: isabelle.boisvert.hsj@ssss.gouv.qc.ca


About this page
Updated on 8/30/2021
Created on 8/30/2021
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