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Wednesday, November 27 2013

Dr. Hélène Decaluwe is awarded a major grant from the CIHR

Montréal, November 27, 2013 – Clinician-scientist in immunology and bone marrow transplantation Dr. Hélène Decaluwe, active in the Viral and Immune Disorders and Cancers research axis at Sainte-Justine University Hospital Center (CHU Sainte-Justine), was awarded a major grant from the Canadian Institutes of Health Research of Canada (CIHR), the federal funding agency for health research. The CIHR has awarded her a grant of nearly $670,000 in support of her research work on gamma(c)-dependent cytokines in CD8 T cell differentiation and exhaustion. The Primary Immune Deficiency Treatment Consortium, funded by the National Institutes of Health (USA), has also granted her a research grant to study CD8 T cell exhaustion in children transplanted for severe combined immunodeficiency. Over the past years, Dr. Decaluwe was awarded support for her projects on leukemia as well from the Leukemia and Lymphoma Society of Canada and the Cole Foundation, through grants that are still ongoing. She is a Clinical Research Scholar of the Fonds de recherche du Québec – Santé, in partnership with the CIHR-funded Canadian Child Health Clinician Scientist Program.

In addition to being a clinician scientist in immunology and bone marrow transplantation as well as a pediatrican and immunologist at CHU Sainte-Justine, Dr. Hélène Decaluwe is a Clinical Assistant Professor in the Department of Pediatrics at Université de Montréal. She studies the mechanisms involved in CD8+ T lymphocytes differentiation, a process paramount to improving immunological memory after vaccination and developing novel cell-based therapies for the treatment of chronic viral infections and cancer. Her work focuses on cell factors that play a key role in eliminating viral pathogens or tumor antigens, as well as in generating and maintaining antigen-specific memory CD8+ T lymphocytes. Dr. Decaluwe also focuses her attention on the function of CD8+ T lymphocytes and their reconstitution kinetics after bone marrow transplantation for leukemias and primary immunodeficiencies.

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Communications, Sainte-Justine University Hospital Research Center

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