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A collection of integrated research platforms in neuroimaging wholly dedicated to children and their families

The IMAGINE Center offers an exceptional facility validated and equipped to measure the child brain from neonatal stages to the end of adolescence. It welcomes children and their families into an accommodating and comfortable space for evaluation under the best conditions for children.

 

 

Brain Imaging at the IMAGINE Center

Over the past decades, various imaging techniques have been developed to observe the human brain's structure and real-time activity. Currently, the IMAGINE Center offers the scientific community two neuroimaging systems for collecting brain data in children within the framework of clinical research projects:

 

Magnetic Resonance Imaging (MRI) system.

MRI is a non-invasive method to capture images of the brain and other head structures by measuring water molecules in tissues using a high magnetic field (3T). By measuring subtle variations in blood flow in different brain areas, we can also assess brain activity and function during specific mental tasks, known as functional MRI. Additionally, diffusion MRI protocols can visualize neural tracts (connections) across brain structures, and spectroscopy protocols measure concentrations of certain metabolites in brain tissues.

 

Electroencephalography (EEG) and near-infrared spectroscopy (NIRS) system.

EEG and NIRS are two non-invasive neuroimaging techniques that record real-time brain activity. One captures the brain's electrical activity, while the other records brain activity by measuring oxygenation levels through light diffusion and absorption in the head tissues. For data acquisition, a very light cap with EEG or NIRS sensors is placed on the child's head and quickly becomes unnoticeable. Brain activity can thus be recorded using both techniques separately or in combination at rest, during cognitive task performance, or in response to auditory, visual, etc., stimuli.

 

Additionally, brain activity from two or more individuals can be simultaneously recorded using a method known as hyperscanning. This approach is used to study real-time neurophysiological processes of social interactions and interpersonal relationships, like brain synchrony during parent-child activities, social interactions between children of different ages, or those with various clinical conditions, etc.

MRI Electroencephalography (EEG) and near-infrared spectroscopy (NIRS) system

Safety and Confidentiality

All neuroimaging techniques available at the IMAGINE Center (MRI, EEG, NIRS) are non-invasive, painless, and without contraindications.

 

Designed to meet the unique needs of pediatric populations, the IMAGINE Center operates in a secure experimental environment and applies neuroimaging protocols tailored to every age group, from birth to adolescence, including vulnerable populations. For example, we have specialized equipment for newborns and very premature infants to ensure safety during transport to the MRI machine and throughout the examination. Advanced MRI protocols are also used to correct for children's head movements, among other things, to minimize the time children spend inside the machine. Parents can safely stay with their child during testing and brain measurement if they wish.

 

All studies conducted at the IMAGINE Center have ethical approval from a Research Ethics Committee (REC), tasked with protecting research participants and ensuring their safety during their participation.

 

The IMAGINE Center guarantees the confidentiality and protection of data collected during study participation. Participating children and their families can rest assured that data protection standards are upheld at all times.

 

Open Science Studies

The IMAGINE Center at CHU Sainte-Justine has established the IMAGINE Center Database to collect and store multimodal brain imaging data for collaborative and innovative research projects. This resource is intended to facilitate and promote research in neurodevelopment, providing valuable insights for researchers in this field. The data collected adhere to the scientific criteria and ethical standards of the IMAGINE Center and relevant institutional guidelines.

Our Research Projects

Visit our dedicated page for pediatric neuroimaging research projects taking place at the IMAGINE Center.

Participating in a Clinical Research Project at the IMAGINE Center

Participants in studies play a central role in health-related research, contributing to its progress. At the IMAGINE Center of CHU Sainte-Justine, they are monitored by a pediatric team of clinical, scientific, and technical professionals. Participate in a research project.

Where to Find Us?

The IMAGINE Center is located at CHU Sainte-Justine
3175, Chemin de la Côte-Sainte-Catherine
H3T 1C5
Montréal, QC Canada

 

For more information, please write to us at the following address: centre.imagine.hsj@ssss.gouv.qc.ca

To prepare and initiate a new study at the IMAGINE Center and for more information regarding our infrastructure and services, please write to us at the following address: centre.imagine.hsj@ssss.gouv.qc.ca

About this page
Updated on 8/6/2024
Created on 7/24/2024
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