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Research Axis
Metabolic and Cardiovascular Health Axis
Research Theme
Genetic and metabolic diseases in Quebec: diagnosis, mechanisms and interventions
Phone
514-518-4311
Online
The Inherited Cardiac Conditions and Sudden Cardiac Death Research Laboratory has as main goal to understand the rhythm abnormalities that have a genetic base, including: ionic channel anomalies (long QT syndrome, Brugada syndrome, cathecholaminergic polymorphic ventricular tachycardia), arrhythmias in the setting of cardiomyopathies (dilated, or hypertrophic cardiomyopathies, arrhythmogenic ventricular dysplasia), and other infectious and metabolic conditions that result in arrythmias. Using new technologies for both diagnosis and treatment, the projects develop within 4 main lines of research:
- Research in the field of potentially lethal arrhythmias during childhood: study of the genotype-phenotype correlation. Investigation on novel cardio-genomic therapies for the different inherited cardiac conditions
- Investigation of risk factors in children from families with history of sudden cardiac death: including models for Cardiac Screening in Children with family history of Sudden cardiac Death
- Pediatric Brugada Syndrome: Creation and maintenance of a international multicentric registry to build up the understanding and knowledge of the early presentation of this condition.
- Development of a bio-bank with a focus on individuals and families that experienced sudden cardiac death and/or potentially lethal arrhythmias
Career Summary
Dr. M Cecilia Gonzalez Corcia obtained a doctorate in medicine from the University of Buenos Aires (Argentina) and completed a specialty in pediatrics at the “R Gutierrez Pediatric Hospital”, University of Buenos Aires. After completing a fellowship in pediatrics, she pursued a training in pediatric cardiology and pediatric electrophysiology at Boston Children's Hospital, Harvard Medical School. In 2012, she relocated to Belgium where she developed the first pediatric electrophysiology program in the country, at the Clinique St Luc, the Catholic University Hospital of Brussels and the UZ of Antwerp. In 2017, she completed a 3-year PhD on Brugada syndrome in young people under the mentorship of Professor Pedro Brugada. From 2018 to 2022, Cecilia served as Head of Pediatric Electrophysiology at Bristol Royal Hospital for Children, where she supported pediatric electrophysiology and inherited heart disease expertise in the South West of the UK. In 2020, she obtained a full scholarship to start a 3-year Masters in Cardio-genomics at Imperial College of London. During her time in UK, she started the project to construct an international Pediatric Brugada Registry. Her main interest is based in the rhythm abnormalities in children and young people including patient with congenital heart disease. She is an expert in the ablation of arrhythmias by cardiac catheterization, and in the diagnosis and management of hereditary arrhythmias. Her research is centered on the use of advanced techniques for the discovery of genes that give rise to arrhythmias, and also exploring the links between genetic data and the possibilities of biomedical applications with the patient and their family. In 2022, she joined the group of Pediatric Cardiologists at Sainte Justine Hospital and the Montreal Clinical Research Institute.
Research Laboratory
Inherited Cardiac Conditions, Pediatric Arrhythmias and Sudden Cardiac Death Laboratory