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CHU Sainte-Justine Research Axes

Activities at the Centre de recherche Azrieli du CHU Sainte-Justine are divided into six axes, each of which in turn is divided into one or more research themes.

Brain and Child Development

The Brain and Child Development axis, composed of neurosciences and developmental psychopathology researchers, initiates biopsychosocial collaborations by studying data from longitudinal studies. The scientists in this axis have acquired international expertise, particularly in the field of sensory systems development, epilepsy etiology and treatment, hypothalamus development and child language development. Among other achievements, studies into psychopathology and child behaviour have led to the creation of an INSERM international unit (French National Institute for Health and Medical Research) and the Centre of Excellence for Early Childhood Development. In the field of neurosciences, researchers have secured major grants from organizations such as Genome Canada and the Canadian Institutes of Health Research (CIHR) to develop a new approach for studies of neurodevelopmental diseases such as schizophrenia, autism or mental retardation. >> Learn more

Musculoskeletal Health, Rehabilitation and Medical Technologies

The expertise of the researchers working in the Musculoskeletal Health, Rehabilitation and Medical Technologies axis is recognized worldwide. The axis promotes a multidisciplinary research approach through fundamental, clinical and rehabilitation research leading to knowledge transfer and clinical innovations aimed at improving children’s well-being. The example of idiopathic scoliosis perfectly illustrates the researchers’ transverse approach, specifically with their development of a diagnostic test. Their objective is to develop innovative and less invasive treatments allowing children and adolescents to live with minimal physical limitations and to detect articular diseases at an early age in order to prevent the effects of these diseases in adulthood. >> Learn more 

Immune Diseases and Cancer

The CHU Sainte-Justine is a world-renowned leader in the field of immune disorders and cancer, most notably regarding acute lymphoblastic leukemia, oncogenetics, the localization of bone marrow stem cells, and the role of the liver in the immune system. CHU Sainte-Justine’s cord blood transplant centre is the largest in the world. Clinical results are excellent and the researchers are known for their innovative work. This research field holds extraordinary potential. Other researchers are developing industry partnerships, including a grant of more than one million dollars from IBM to accelerate research into the causes of childhood leukemia and other complex pediatric diseases with the goal of developing individualized treatment strategies. >> Learn more

Infectious Diseases and Acute Care

CHU Sainte-Justine is a mother-child reference centre for the prevention, diagnosis and management of infectious diseases that affect pediatric patients and pregnant women in the Province of Quebec. It is also the main centre for pediatric emergency medicine, trauma, and intensive care. Our institution is the only one in Quebec to group these specific fields of expertise. Given this status, researchers in the Infectious Diseases and Acute Care axis work to help prevent, offer new therapies and cure infectious diseases, in addition to disorders occurring in critical care situations. >> Learn more

Fetomaternal and Neonatal Pathologies

The Fetomaternal and Neonatal Pathologies axis builds on the unique structure of the CHU Sainte-Justine Research Centre through the study of abnormalities in embryonic, fetal and neonatal development. The CHU Sainte-Justine is one of the most dynamic university hospital centres in Canada in the field of perinatal research. CHU Sainte-Justine’s researchers are interested in various aspects of fetomaternal health, such as retinopathy of prematurity, cardiovascular pregnancy paradox, aortic isthmus and the effects of antidepressants on pregnancy. >> Learn more

Metabolic and Cardiovascular Health

The Metabolic and Cardiovascular Health axis seeks to understand, prevent and intervene in important metabolic issues ranging from the fetal period through to adulthood. Our researchers are working on genetic disease prevalence and distribution, founder effects and genetic variance in Québec in addition to the functional dissection of intestinal lipid transport. A team of researchers is also studying North American Indian childhood cirrhosis (NAIC/CIRH1A), a disease that is specific to NW Québec. >> Learn more

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Updated on 12/13/2023
Created on 6/19/2015
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